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Gene Information
Gene ID:90203
Symbol:SNX21
Full Name:sorting nexin family member 21
Alias:C20orf161|MGC29895|PP3993|SNX-L|dJ337O18.4
Organism:Homo sapiens (Human)
Chromosome:20
Genetic Location:20q13.12
Physical Location:43895876-43905320 on NC_000020.9
Gene Type:protein-coding
Orthologs:This gene has Fly: 33466 ortholog(s) in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D20S119  43082264
Region:41082264-45082264
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001042632.1NP_001036097.1NC_000020.9 range: 43895876..43905320
NM_001042633.1NP_001036098.1NC_000020.9 range: 43895876..43905320
NM_033421.2NP_219489.1NC_000020.9 range: 43895876..43905320
NM_152897.1NP_690857.1NC_000020.9 range: 43895876..43905320
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005515protein bindingMolecular FunctionIEA
GO:0035091phosphoinositide bindingMolecular FunctionIEA
GO:0007154cell communicationBiological ProcessIEA
GO:0015031protein transportBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:90203
HGNC:16154
Ensembl:ENSG00000124104
MIM:
HPRD:16641
HuGE Navigator:90203
dbSNP:SNX21
GeneCard:SNX21
AceView:SNX21