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Gene Information
Gene ID:92235
Symbol:DUSP27
Full Name:dual specificity phosphatase 27 (putative)
Organism:Homo sapiens (Human)
Chromosome:1
Genetic Location:1q22-q24
Physical Location:165330710-165365025 on NC_000001.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D1S2878  163669990
Region:163669990-165871089
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_001080426.1NP_001073895.1NC_000001.9 range: 165330710..165365025
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0008138protein tyrosine/serine/threonine phosphatase activityMolecular FunctionIEA
GO:0016791phosphoric monoester hydrolase activityMolecular FunctionIEA
GO:0006470protein amino acid dephosphorylationBiological ProcessIEA
Other Database Cross Links
NCBI Entrez Gene:92235
HGNC:25034
Ensembl:ENSG00000198842
MIM:
HPRD:
HuGE Navigator:92235
dbSNP:DUSP27
GeneCard:DUSP27
AceView:DUSP27