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Gene Information
Gene ID:9423
Symbol:NTN1
Full Name:netrin 1
Alias:NTN1L
Organism:Homo sapiens (Human)
Chromosome:17
Genetic Location:17p13-p12
Physical Location:8865583-9088041 on NC_000017.9
Gene Type:protein-coding
Orthologs:This gene has no orthologs in other dataset(s).
Gene in Ethanol Study Datasets
Linkage Dataset
MarkerLODP valueLocation (bp)
D17S1852  10456226
Region:8456226-12456226
Phenotype:Alcoholism phenotype along with age, gender, and P300 or constraint
Name:15211641
Method:Linkage
Publication:Hill et al. Am J Med Genet B Neuropsychiatr Genet. (2004) A genome wide search for alcoholism susceptibility genes. PubMed
Summary:A total of 360 markers for 22 autosomes were spaced at an average distance of 9.4cMand genotyping performed for 330 members of these multiplex families. Extensive clinical data, personality variation, and event-related potential characteristics were available for reducing heterogeneity and detecting robust linkage signals. Multipoint linkage analysis using different analytic strategies give strong support for loci on chromosomes 1, 2, 6, 7, 10, 12, 14, 16, and 17. Thirty five markers with LOD score >2.0 at baseline using the binary alcoholism phenotype along with age, gender, and P300 or constraint (Table III). Here we listed the genes between two near markers or genes near a separate marker (within 2Mb).
Gene Refseq Sequence Annotation
mRNAProteinReference assembly Genomic
NM_004822.2NP_004813.2NC_000017.9 range: 8865583..9088041
Gene Ontology (GO) Annotation
GO IDGO TermCategoryEvidence (PubMed)
GO:0005576extracellular regionCellular ComponentIEA
GO:0005578proteinaceous extracellular matrixCellular ComponentIEA
GO:0005615extracellular spaceCellular ComponentNR
GO:0005625soluble fractionCellular ComponentNR
GO:0005515protein bindingMolecular FunctionIEA
GO:0006915apoptosisBiological ProcessIEA
GO:0006928cell motilityBiological ProcessNR
GO:0007267cell-cell signalingBiological ProcessNR
GO:0007399nervous system developmentBiological ProcessNR
Other Database Cross Links
NCBI Entrez Gene:9423
HGNC:8029
Ensembl:ENSG00000065320
MIM:601614
HPRD:03368
HuGE Navigator:9423
dbSNP:NTN1
GeneCard:NTN1
AceView:NTN1