| Gene Information |
| Gene ID: | | 945 |
| Symbol: | | CD33 |
| Full Name: | | CD33 molecule |
| Alias: | | FLJ00391|SIGLEC-3|SIGLEC3|p67 |
| Organism: | | Homo sapiens (Human) |
| Chromosome: | | 19 |
| Genetic Location: | | 19q13.3 |
| Physical Location: | | 56420146-56435085 on NC_000019.8 |
| Gene Type: | | protein-coding |
| Orthologs: | | This gene has no orthologs in other dataset(s). |
|
| Gene in Ethanol Study Datasets |
| Gene Information | | Original ID1: | | BI910568 | | Fold Change: | | 0.63 | | P Value: | | 2.00E-03 | | Tissue: | | Prefrontal cortex |
| | Dataset Information | | Name: | | 15816859 | | Method: | | Microarray | | Tissue: | | Prefrontal cortex and nucleus accumbens | | Phenotype: | | Alcohol dependence (AD)/Alcohol abuse/Alcoholism | | Publication: | | Flatscher-Bader et al. J Neurochem.(2005) Alcohol-responsive genes in the frontal cortex and nucleus accumbens of human alcoholics. PubMed | | Summary: | | Genes with a mean fold change > 1.5 or < 0.7 were selected and annotated. Values are taken from microarray analysis and represent mean ratios of alcoholic cases compared with matched control cases(n = 6). P values were from t-test. |
| | Gene Information | | | Dataset Information | | Name: | | Literature Search | | Method: | | Literature search | | Summary: | | We search all human protein coding gene names and the keywords Alcohol or Ethanol or Alcoholism in the title or abstract of all PUBMED publications. For those gene name less than 3 characters or search result hits more than 100, we use the full name to search again and manually check the results to reduce false positive. |
|
|
| Gene Refseq Sequence Annotation |
|
| Gene Ontology (GO) Annotation |
| GO ID | GO Term | Category | Evidence (PubMed) | |
| GO:0005886 | plasma membrane | Cellular Component | TAS (3139766) | |
| GO:0005887 | integral to plasma membrane | Cellular Component | TAS (3139766) | |
| GO:0004872 | receptor activity | Molecular Function | TAS (10611343) | |
| GO:0005515 | protein binding | Molecular Function | IEA | |
| GO:0005529 | sugar binding | Molecular Function | IEA | |
| GO:0007155 | cell adhesion | Biological Process | NAS (10611343) | |
| GO:0007165 | signal transduction | Biological Process | TAS (10611343) | |
| GO:0007267 | cell-cell signaling | Biological Process | TAS (10611343) | |
| GO:0008285 | negative regulation of cell proliferation | Biological Process | TAS (10611343) | |
|
| Other Database Cross Links |
| NCBI Entrez Gene: | | 945 |
| HGNC: | | 1659 |
| Ensembl: | | ENSG00000105383 |
| MIM: | | 159590 |
| HPRD: | | 01165 |
| HuGE Navigator: | | 945 |
| dbSNP: | | CD33 |
| GeneCard: | | CD33 |
| AceView: | | CD33 |
