ERGR - Ethanol-Related Gene Resource

Gene Information

Gene ID:

Symbol:

Aof2

Full Name:

amine oxidase (flavin containing) domain 2

Alias:

1810043O07Rik|AA408884|D4Ertd478e|KDM1|LSD1|mKIAA0601

Organism:

Mus musculus (Mouse)

Chromosome:

Genetic Location:

4 D3|4 66.75 cM

Physical Location:

136106471-136158624 on NC_000070.5, complement

Gene Type:

protein-coding

Human Ortholog:

GeneID: 23028 Symbol (Name): AOF2 (amine oxidase (flavin containing) domain 2)

Ortholog Status:

The human GeneID 23028 is not in current human dataset.

Gene in Ethanol Study Datasets

QTL Information

QTL	Phenotype	Chr	Peak (cM)	LOD	P Value	Range	Status	QTL Link
Ap3q	Alcohol Preference Drinking	4	75	65-ter (cM)	4.6		Significant	PARC

Gene Refseq Sequence Annotation

mRNA	Protein	Reference assembly Genomic
NM_133872.1	NP_598633.1	NC_000070.5 range: 136106471..136158624, complement

Gene Ontology (GO) Annotation

GO ID	GO Term	Category	Evidence (PubMed)
GO:0005634	nucleus	Cellular Component	IEA
GO:0005667	transcription factor complex	Cellular Component	IDA (17392792)
GO:0008134	transcription factor binding	Molecular Function	IPI (17392792)
GO:0003700	transcription factor activity	Molecular Function	IDA (17392792)
GO:0016491	oxidoreductase activity	Molecular Function	IEA
GO:0009055	electron carrier activity	Molecular Function	IEA
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (17392792)
GO:0021983	pituitary gland development	Biological Process	IMP (17392792)
GO:0016568	chromatin modification	Biological Process	IEA
GO:0008283	cell proliferation	Biological Process	IMP (17392792)
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process	IMP (17392792)
GO:0006355	regulation of transcription, DNA-dependent	Biological Process	IEA
GO:0006350	transcription	Biological Process	IEA
GO:0001701	in utero embryonic development	Biological Process	IMP (17392792)
GO:0046886	positive regulation of hormone biosynthetic process	Biological Process	IMP (17392792)