| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44046891 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046890 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046766 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046889 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046888 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046887 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046765 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44041222 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046886 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ACACB |
|---|---|
| DrugBank ID | DB00121 |
| Drug Name | Biotin |
| Target ID | BE0000702 |
| UniProt ID | O00763 |
| Regulation Type | cofactor |
| PubMed IDs | 17477831; 16772434 |
| Citations | Liu Y, Zalameda L, Kim KW, Wang M, McCarter JD: Discovery of acetyl-coenzyme A carboxylase 2 inhibitors: comparison of a fluorescence intensity-based phosphate assay and a fluorescence polarization-based ADP Assay for high-throughput screening. Assay Drug Dev Technol. 2007 Apr;5(2):225-35.@@Hassan YI, Zempleni J: Epigenetic regulation of chromatin structure and gene function by biotin. J Nutr. 2006 Jul;136(7):1763-5. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Biotin and derivatives |
| SMILES | [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2 |
| Pathways | Mitochondrial Complex II Deficiency; 3-Methylglutaconic Aciduria Type III; 2-Ketoglutarate Dehydrogenase Complex Deficiency; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Isovaleric Aciduria; Pyruvate Carboxylase Deficiency; Warburg Effect; Isobutyryl-CoA Dehydrogenase Deficiency; Biotin Metabolism; Fructose-1,6-diphosphatase Deficiency; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Propionic Acidemia; Transfer of Acetyl Groups into Mitochondria; Malonic Aciduria; 2-Hydroxyglutric Aciduria (D and L Form); 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Congenital Lactic Acidosis; 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency; Fumarase Deficiency; Succinic Semialdehyde Dehydrogenase Deficiency; Alanine Metabolism; Methylmalonic Aciduria; 3-Methylglutaconic Aciduria Type IV; Lactic Acidemia; Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease; Primary Hyperoxaluria Type I; Triosephosphate Isomerase; The Oncogenic Action of 2-Hydroxyglutarate; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease |
| PharmGKB | PA448625 |
| ChEMBL | CHEMBL857 |
