| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44046891 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046890 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046766 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046889 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046888 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046887 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046765 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44041222 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
| TVIS44046886 | HTLV-1 | ENSG00000076555.16 | protein_coding | ACACB | No | No | 32 | O00763 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ACACB |
|---|---|
| DrugBank ID | DB00173 |
| Drug Name | Adenine |
| Target ID | BE0000702 |
| UniProt ID | O00763 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 8318018; 2880560; 12829626; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Rasmussen JT, Rosendal J, Knudsen J: Interaction of acyl-CoA binding protein (ACBP) on processes for which acyl-CoA is a substrate, product or inhibitor. Biochem J. 1993 Jun 15;292 ( Pt 3):907-13.@@Witters LA, Mendel DB, Colliton JW: Modulation of acetyl-CoA carboxylase by inhibitors of IMP dehydrogenase: implications for insulin regulation. Arch Biochem Biophys. 1987 Jan;252(1):130-5.@@Itani SI, Saha AK, Kurowski TG, Coffin HR, Tornheim K, Ruderman NB: Glucose autoregulates its uptake in skeletal muscle: involvement of AMP-activated protein kinase. Diabetes. 2003 Jul;52(7):1635-40.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved; Nutraceutical |
| Direct Classification | 6-aminopurines |
| SMILES | NC1=C2NC=NC2=NC=N1 |
| Pathways | Gout or Kelley-Seegmiller Syndrome; Purine Metabolism; Lesch-Nyhan Syndrome (LNS); Myoadenylate Deaminase Deficiency; Molybdenum Cofactor Deficiency; Adenine Phosphoribosyltransferase Deficiency (APRT); Mercaptopurine Action Pathway; Xanthinuria Type I; Azathioprine Action Pathway; AICA-Ribosiduria; Thioguanine Action Pathway; Mitochondrial DNA Depletion Syndrome; Adenosine Deaminase Deficiency; Xanthine Dehydrogenase Deficiency (Xanthinuria); Purine Nucleoside Phosphorylase Deficiency; Adenylosuccinate Lyase Deficiency; Xanthinuria Type II |
| PharmGKB | PA448048 |
| ChEMBL | CHEMBL226345 |
