Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30085360HIVENSG00000057593.14protein_codingF7NoNo2155F5H8B0
P08709
TCGA Plot Options
Drug Information
GeneF7
DrugBank IDDB00036
Drug NameCoagulation factor VIIa Recombinant Human
Target IDBE0000333
UniProt IDP08709
Regulation Type
PubMed IDs10388743; 11735107; 12525826; 15907148; 16370916
CitationsPerera L, Darden TA, Pedersen LG: Probing the structural changes in the light chain of human coagulation factor VIIa due to tissue factor association. Biophys J. 1999 Jul;77(1):99-113.@@Shapiro A: Inhibitor treatment: state of the art. Semin Hematol. 2001 Oct;38(4 Suppl 12):26-34.@@Shapiro A: Inhibitor treatment: state of the art. Dis Mon. 2003 Jan;49(1):22-38.@@Siddiqui MA, Scott LJ: Recombinant factor VIIa (Eptacog Alfa): a review of its use in congenital or acquired haemophilia and other congenital bleeding disorders. Drugs. 2005;65(8):1161-77.@@Rizoli SB, Chughtai T: The emerging role of recombinant activated Factor VII (rFVIIa) in the treatment of blunt traumatic haemorrhage. Expert Opin Biol Ther. 2006 Jan;6(1):73-81.
GroupsApproved
Direct ClassificationPeptides
SMILES
Pathways
PharmGKBPA164748389
ChEMBL