| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30065189 | HIV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS20061305 | HPV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS20046313 | HPV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS20067763 | HPV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS44025744 | HTLV-1 | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS44049006 | HTLV-1 | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS44049007 | HTLV-1 | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GCLC |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000166 |
| UniProt ID | P48506 |
| Regulation Type | substrate |
| PubMed IDs | 22995213 |
| Citations | Lu SC: Glutathione synthesis. Biochim Biophys Acta. 2013 May;1830(5):3143-53. doi: 10.1016/j.bbagen.2012.09.008. Epub 2012 Sep 17. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
