| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30065189 | HIV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS20061305 | HPV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS20046313 | HPV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS20067763 | HPV | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS44025744 | HTLV-1 | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS44049006 | HTLV-1 | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
| TVIS44049007 | HTLV-1 | ENSG00000001084.13 | protein_coding | GCLC | No | No | 2729 | E1CEI4 P48506 Q14TF0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GCLC |
|---|---|
| DrugBank ID | DB00151 |
| Drug Name | Cysteine |
| Target ID | BE0000166 |
| UniProt ID | P48506 |
| Regulation Type | |
| PubMed IDs | 15695431; 17615559 |
| Citations | Ashida H, Sawa Y, Shibata H: Cloning, biochemical and phylogenetic characterizations of gamma-glutamylcysteine synthetase from Anabaena sp. PCC 7120. Plant Cell Physiol. 2005 Apr;46(4):557-62. Epub 2005 Feb 2.@@Srivastava S, Chan C: Application of metabolic flux analysis to identify the mechanisms of free fatty acid toxicity to human hepatoma cell line. Biotechnol Bioeng. 2008 Feb 1;99(2):399-410. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Cysteine and derivatives |
| SMILES | N[C@@H](CS)C(O)=O |
| Pathways | Amiloride Action Pathway; gamma-Glutamyltranspeptidase Deficiency; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Hydroflumethiazide Action Pathway; Bumetanide Action Pathway; Polythiazide Action Pathway; Ethacrynic Acid Action Pathway; Cyclothiazide Action Pathway; Trichlormethiazide Action Pathway; gamma-Glutamyltransferase Deficiency; Methionine Adenosyltransferase Deficiency; Glutamate Metabolism; Chlorothiazide Action Pathway; Pantothenate and CoA Biosynthesis; Non-Ketotic Hyperglycinemia; 2-Hydroxyglutric Aciduria (D and L Form); Indapamide Action Pathway; Hyperinsulinism-Hyperammonemia Syndrome; Iminoglycinuria; Taurine and Hypotaurine Metabolism; Glycine and Serine Metabolism; Chlorthalidone Action Pathway; Bendroflumethiazide Action Pathway; Methionine Metabolism; Eplerenone Action Pathway; Cystathionine beta-Synthase Deficiency; Glucose Transporter Defect (SGLT2); Spironolactone Action Pathway; Sarcosinemia; Quinethazone Action Pathway |
| PharmGKB | PA449173 |
| ChEMBL | CHEMBL863 |
