| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20050040 | HPV | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS20045630 | HPV | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS20065901 | HPV | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS20027492 | HPV | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS20037070 | HPV | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS20045213 | HPV | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS44002387 | HTLV-1 | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS44001616 | HTLV-1 | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS44020408 | HTLV-1 | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
| TVIS44026578 | HTLV-1 | ENSG00000053918.20 | protein_coding | KCNQ1 | No | No | 3784 | P51787 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNQ1 |
|---|---|
| DrugBank ID | DB01244 |
| Drug Name | Bepridil |
| Target ID | BE0000672 |
| UniProt ID | P51787 |
| Regulation Type | inhibitor |
| PubMed IDs | 10860024; 14716203; 9765513 |
| Citations | Chouabe C, Drici MD, Romey G, Barhanin J: Effects of calcium channel blockers on cloned cardiac K+ channels IKr and IKs. Therapie. 2000 Jan-Feb;55(1):195-202.@@Yumoto Y, Horie M, Kubota T, Ninomiya T, Kobori A, Takenaka K, Takano M, Niwano S, Izumi T: Bepridil block of recombinant human cardiac IKs current shows a time-dependent unblock. J Cardiovasc Pharmacol. 2004 Feb;43(2):178-82.@@Chouabe C, Drici MD, Romey G, Barhanin J, Lazdunski M: HERG and KvLQT1/IsK, the cardiac K+ channels involved in long QT syndromes, are targets for calcium channel blockers. Mol Pharmacol. 1998 Oct;54(4):695-703. |
| Groups | Approved; Withdrawn |
| Direct Classification | Phenylbenzamines |
| SMILES | CC(C)COCC(CN(CC1=CC=CC=C1)C1=CC=CC=C1)N1CCCC1 |
| Pathways | |
| PharmGKB | PA164754755 |
| ChEMBL | CHEMBL1008 |
