| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004594 | HBV | ENSG00000175591.12 | protein_coding | P2RY2 | No | No | 5029 | P41231 |
| TVIS10026652 | HBV | ENSG00000175591.12 | protein_coding | P2RY2 | No | No | 5029 | P41231 |
| TVIS10052252 | HBV | ENSG00000175591.12 | protein_coding | P2RY2 | No | No | 5029 | P41231 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | P2RY2 |
|---|---|
| DrugBank ID | DB04786 |
| Drug Name | Suramin |
| Target ID | BE0002401 |
| UniProt ID | P41231 |
| Regulation Type | antagonist |
| PubMed IDs | 8762097; 9647463; 16388598; 9112981; 11132624 |
| Citations | Charlton SJ, Brown CA, Weisman GA, Turner JT, Erb L, Boarder MR: PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors. Br J Pharmacol. 1996 Jun;118(3):704-10.@@Bogdanov YD, Wildman SS, Clements MP, King BF, Burnstock G: Molecular cloning and characterization of rat P2Y4 nucleotide receptor. Br J Pharmacol. 1998 Jun;124(3):428-30.@@Trujillo CA, Nery AA, Martins AH, Majumder P, Gonzalez FA, Ulrich H: Inhibition mechanism of the recombinant rat P2X(2) receptor in glial cells by suramin and TNP-ATP. Biochemistry. 2006 Jan 10;45(1):224-33.@@Churchill GC, Louis CF: Stimulation of P2U purinergic or alpha 1A adrenergic receptors mobilizes Ca2+ in lens cells. Invest Ophthalmol Vis Sci. 1997 Apr;38(5):855-65.@@Homma R, Kimoto T, Niimura Y, Krivosheev A, Hara T, Ohta Y, Kawato S: Real-time fluorescence analysis on molecular mechanisms for regulation of cytochrome P450scc activity upon steroidogenic stimulation in adrenocortical cells. J Inorg Biochem. 2000 Nov;82(1-4):171-80. |
| Groups | Investigational |
| Direct Classification | Benzanilides |
| SMILES | CC1=C(NC(=O)C2=CC(NC(=O)NC3=CC=CC(=C3)C(=O)NC3=C(C)C=CC(=C3)C(=O)NC3=C4C(C=C(C=C4S(O)(=O)=O)S(O)(=O)=O)=C(C=C3)S(O)(=O)=O)=CC=C2)C=C(C=C1)C(=O)NC1=C2C(C=C(C=C2S(O)(=O)=O)S(O)(=O)=O)=C(C=C1)S(O)(=O)=O |
| Pathways | |
| PharmGKB | PA10292 |
| ChEMBL | CHEMBL265502 |
