| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20028519 | HPV | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS20070103 | HPV | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS20028518 | HPV | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS20069511 | HPV | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS20040907 | HPV | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS44032812 | HTLV-1 | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS44031657 | HTLV-1 | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
| TVIS44048357 | HTLV-1 | ENSG00000102230.14 | protein_coding | PCYT1B | No | No | 9468 | Q9Y5K3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PCYT1B |
|---|---|
| DrugBank ID | DB00122 |
| Drug Name | Choline |
| Target ID | BE0000494 |
| UniProt ID | Q9Y5K3 |
| Regulation Type | product of |
| PubMed IDs | 17139284; 17016423; 15798219 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Wang L, Magdaleno S, Tabas I, Jackowski S: Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a). Mol Cell Biol. 2005 Apr;25(8):3357-63. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Cholines |
| SMILES | C[N+](C)(C)CCO |
| Pathways | Phosphatidylcholine Biosynthesis PC(14:0/20:0); Phosphatidylcholine Biosynthesis PC(14:0/20:4(5Z,8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/20:3(8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/16:0); Phosphatidylcholine Biosynthesis PC(14:0/20:5(5Z,8Z,11Z,14Z,17Z)); Phosphatidylcholine Biosynthesis PC(14:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/16:0); Phosphatidylcholine Biosynthesis PC(14:0/20:2(11Z,14Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/22:2(13Z,16Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/24:0); Phosphatidylcholine Biosynthesis PC(14:0/15:0); Phosphatidylcholine Biosynthesis PC(15:0/14:0); Phosphatidylcholine Biosynthesis PC(15:0/20:4(5Z,8Z,11Z,14Z)); Phosphatidylcholine Biosynthesis PC(15:0/22:6(4Z,7Z,10Z,13Z,16Z,19Z)); Betaine Metabolism; Phosphatidylcholine Biosynthesis PC(14:0/20:1(11Z)); Phosphatidylcholine Biosynthesis PC(16:0/14:0); Phosphatidylcholine Biosynthesis PC(15:0/22:0); Phosphatidylcholine Biosynthesis PC(14:0/22:5(4Z,7Z,10Z,13Z,16Z)); Phosphatidylcholine Biosynthesis PC(15:0/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(14:1(9Z)/14:0); Phosphatidylcholine Biosynthesis PC(15:0/20:1(11Z)); Phosphatidylcholine Biosynthesis PC(14:0/18:2(9Z,12Z)); Phosphatidylcholine Biosynthesis PC(14:0/14:0); Cystathionine beta-Synthase Deficiency; Phosphatidylcholine Biosynthesis PC(14:0/16:1(9Z)); Phosphatidylcholine Biosynthesis PC(15:0/18:0); Sarcosine Oncometabolite Pathway; Phosphatidylcholine Biosynthesis PC(14:1(9Z)/18:3(9Z,12Z,15Z)) |
| PharmGKB | PA448976 |
| ChEMBL | CHEMBL920 |
