| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048832 | HBV | ENSG00000101000.6 | protein_coding | PROCR | No | No | 10544 | Q9UNN8 |
| TVIS10048833 | HBV | ENSG00000101000.6 | protein_coding | PROCR | No | No | 10544 | Q9UNN8 |
| TVIS20008217 | HPV | ENSG00000101000.6 | protein_coding | PROCR | No | No | 10544 | Q9UNN8 |
| TVIS20009595 | HPV | ENSG00000101000.6 | protein_coding | PROCR | No | No | 10544 | Q9UNN8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PROCR |
|---|---|
| DrugBank ID | DB00055 |
| Drug Name | Drotrecogin alfa |
| Target ID | BE0001161 |
| UniProt ID | Q9UNN8 |
| Regulation Type | |
| PubMed IDs | 9529319; 12871285; 12353077; 17566522; 15118520 |
| Citations | Fukudome K, Ye X, Tsuneyoshi N, Tokunaga O, Sugawara K, Mizokami H, Kimoto M: Activation mechanism of anticoagulant protein C in large blood vessels involving the endothelial cell protein C receptor. J Exp Med. 1998 Apr 6;187(7):1029-35.@@Ruf W, Dorfleutner A, Riewald M: Specificity of coagulation factor signaling. J Thromb Haemost. 2003 Jul;1(7):1495-503.@@Castellino FJ, Liang Z, Volkir SP, Haalboom E, Martin JA, Sandoval-Cooper MJ, Rosen ED: Mice with a severe deficiency of the endothelial protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge. Thromb Haemost. 2002 Sep;88(3):462-72.@@Cerchiara E, Tirindelli MC, Giannetti B, Dicuonzo G, Avvisati G: [The numerous properties of the anticoagulant protein C]. Clin Ter. 2007 Mar-Apr;158(2):181-7.@@Liaw PC: Endogenous protein C activation in patients with severe sepsis. Crit Care Med. 2004 May;32(5 Suppl):S214-8. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA131548935 |
| ChEMBL |
