Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10025795HBVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS10016393HBVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS30077911HIVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS30022865HIVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS30022866HIVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS20047912HPVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS44032180HTLV-1ENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS44005231HTLV-1ENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS44037114HTLV-1ENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TCGA Plot Options
Drug Information
GenePTAFR
DrugBank IDDB02261
Drug NamePlatelet Activating Factor
Target IDBE0005561
UniProt IDP25105
Regulation Type
PubMed IDs11529688; 16386258
CitationsQian C, Hwang SB, Libertine-Garahan L, Eckman JB, Cai X, Scannell RT, Yeh CG: Anti-inflammatory activities of LDP-392, a dual PAF receptor antagonist and 5-lipoxygenase inhibitor. Pharmacol Res. 2001 Sep;44(3):213-20.@@Pegorier S, Stengel D, Durand H, Croset M, Ninio E: Oxidized phospholipid: POVPC binds to platelet-activating-factor receptor on human macrophages. Implications in atherosclerosis. Atherosclerosis. 2006 Oct;188(2):433-43. Epub 2005 Dec 28.
GroupsExperimental
Direct Classification1-alkyl,2-acetylglycero-3-phosphocholines
SMILESCCCCCCCCCCCCCCCCOC[C@H](CO[P@@]([O-])(=O)OCC[N+](C)(C)C)OC(C)=O
Pathways
PharmGKB
ChEMBLCHEMBL1235246