Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10025795HBVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS10016393HBVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS30077911HIVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS30022865HIVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS30022866HIVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS20047912HPVENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS44032180HTLV-1ENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS44005231HTLV-1ENSG00000169403.12protein_codingPTAFRNoNo5724P25105
TVIS44037114HTLV-1ENSG00000169403.12protein_codingPTAFRNoNo5724P25105
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Drug Information
GenePTAFR
DrugBank IDDB11614
Drug NameRupatadine
Target IDBE0005561
UniProt IDP25105
Regulation Typeantagonist
PubMed IDs8996188
CitationsMerlos M, Giral M, Balsa D, Ferrando R, Queralt M, Puigdemont A, Garcia-Rafanell J, Forn J: Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF). J Pharmacol Exp Ther. 1997 Jan;280(1):114-21.
GroupsApproved
Direct ClassificationBenzocycloheptapyridines
SMILESCC1=CC(CN2CCC(CC2)=C2C3=CC=C(Cl)C=C3CCC3=C2N=CC=C3)=CN=C1
PathwaysRupatadine H1-Antihistamine Action
PharmGKBPA165107052
ChEMBLCHEMBL91397