| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44003701 | HTLV-1 | ENSG00000088826.18 | protein_coding | SMOX | No | No | 54498 | Q9NWM0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SMOX |
|---|---|
| DrugBank ID | DB00127 |
| Drug Name | Spermine |
| Target ID | BE0000566 |
| UniProt ID | Q9NWM0 |
| Regulation Type | ligand |
| PubMed IDs | 11258887; 12141946; 12477380; 12727196; 15133083 |
| Citations | Binda C, Angelini R, Federico R, Ascenzi P, Mattevi A: Structural bases for inhibitor binding and catalysis in polyamine oxidase. Biochemistry. 2001 Mar 6;40(9):2766-76.@@Vujcic S, Diegelman P, Bacchi CJ, Kramer DL, Porter CW: Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin. Biochem J. 2002 Nov 1;367(Pt 3):665-75.@@Vujcic S, Liang P, Diegelman P, Kramer DL, Porter CW: Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. Biochem J. 2003 Feb 15;370(Pt 1):19-28.@@Wang Y, Murray-Stewart T, Devereux W, Hacker A, Frydman B, Woster PM, Casero RA Jr: Properties of purified recombinant human polyamine oxidase, PAOh1/SMO. Biochem Biophys Res Commun. 2003 May 16;304(4):605-11.@@Bacchi CJ, Rattendi D, Faciane E, Yarlett N, Weiss LM, Frydman B, Woster P, Wei B, Marton LJ, Wittner M: Polyamine metabolism in a member of the phylum Microspora (Encephalitozoon cuniculi): effects of polyamine analogues. Microbiology. 2004 May;150(Pt 5):1215-24. |
| Groups | Experimental; Nutraceutical |
| Direct Classification | Dialkylamines |
| SMILES | NCCCNCCCCNCCCN |
| Pathways | Spermidine and Spermine Biosynthesis |
| PharmGKB | PA164781199 |
| ChEMBL | CHEMBL23194 |
