| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44003701 | HTLV-1 | ENSG00000088826.18 | protein_coding | SMOX | No | No | 54498 | Q9NWM0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SMOX |
|---|---|
| DrugBank ID | DB04188 |
| Drug Name | MDL72527 |
| Target ID | BE0000566 |
| UniProt ID | Q9NWM0 |
| Regulation Type | inhibitor |
| PubMed IDs | 31991839; 30686964 |
| Citations | Liu F, Saul AB, Pichavaram P, Xu Z, Rudraraju M, Somanath PR, Smith SB, Caldwell RB, Narayanan SP: Pharmacological Inhibition of Spermine Oxidase Reduces Neurodegeneration and Improves Retinal Function in Diabetic Mice. J Clin Med. 2020 Jan 25;9(2). pii: jcm9020340. doi: 10.3390/jcm9020340.@@Pichavaram P, Palani CD, Patel C, Xu Z, Shosha E, Fouda AY, Caldwell RB, Narayanan SP: Targeting Polyamine Oxidase to Prevent Excitotoxicity-Induced Retinal Neurodegeneration. Front Neurosci. 2019 Jan 10;12:956. doi: 10.3389/fnins.2018.00956. eCollection 2018. |
| Groups | Experimental |
| Direct Classification | Dialkylamines |
| SMILES | C=C=CCNCCCCNCC=C=C |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL417844 |
