| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20031141 | HPV | ENSG00000159164.10 | protein_coding | SV2A | No | No | 9900 | Q7L0J3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SV2A |
|---|---|
| DrugBank ID | DB01202 |
| Drug Name | Levetiracetam |
| Target ID | BE0000993 |
| UniProt ID | Q7L0J3 |
| Regulation Type | agonist |
| PubMed IDs | 15210974; 15367040; 18072813; 17461889 |
| Citations | Lynch BA, Lambeng N, Nocka K, Kensel-Hammes P, Bajjalieh SM, Matagne A, Fuks B: The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9861-6. Epub 2004 Jun 21.@@Stahl SM: Psychopharmacology of anticonvulsants: levetiracetam as a synaptic vesicle protein modulator. J Clin Psychiatry. 2004 Sep;65(9):1162-3.@@Johannessen Landmark C: Antiepileptic drugs in non-epilepsy disorders: relations between mechanisms of action and clinical efficacy. CNS Drugs. 2008;22(1):27-47.@@De Smedt T, Raedt R, Vonck K, Boon P: Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data. CNS Drug Rev. 2007 Spring;13(1):43-56. |
| Groups | Approved |
| Direct Classification | Alpha amino acids and derivatives |
| SMILES | CC[C@H](N1CCCC1=O)C(N)=O |
| Pathways | |
| PharmGKB | PA450206 |
| ChEMBL | CHEMBL1286 |
