| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10046767 | HBV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30004885 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30016238 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30003676 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30008618 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30008619 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30003677 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30018705 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30060695 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
| TVIS30060696 | HIV | ENSG00000109320.14 | protein_coding | NFKB1 | No | No | 4790 | P19838 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | NFKB1 |
|---|---|
| DrugBank ID | DB08814 |
| Drug Name | Triflusal |
| Target ID | BE0001086 |
| UniProt ID | P19838 |
| Regulation Type | antagonist |
| PubMed IDs | 15678110; 19465361; 18317243; 17194886 |
| Citations | Zhang W, Potrovita I, Tarabin V, Herrmann O, Beer V, Weih F, Schneider A, Schwaninger M: Neuronal activation of NF-kappaB contributes to cell death in cerebral ischemia. J Cereb Blood Flow Metab. 2005 Jan;25(1):30-40.@@Anninos H, Andrikopoulos G, Pastromas S, Sakellariou D, Theodorakis G, Vardas P: Triflusal: an old drug in modern antiplatelet therapy. Review of its action, use, safety and effectiveness. Hellenic J Cardiol. 2009 May-Jun;50(3):199-207.@@Gomez-Isla T, Blesa R, Boada M, Clarimon J, Del Ser T, Domenech G, Ferro JM, Gomez-Anson B, Manubens JM, Martinez-Lage JM, Munoz D, Pena-Casanova J, Torres F: A randomized, double-blind, placebo controlled-trial of triflusal in mild cognitive impairment: the TRIMCI study. Alzheimer Dis Assoc Disord. 2008 Jan-Mar;22(1):21-9. doi: 10.1097/WAD.0b013e3181611024.@@Whitehead SN, Bayona NA, Cheng G, Allen GV, Hachinski VC, Cechetto DF: Effects of triflusal and aspirin in a rat model of cerebral ischemia. Stroke. 2007 Feb;38(2):381-7. Epub 2006 Dec 28. |
| Groups | Approved; Investigational |
| Direct Classification | Acylsalicylic acids |
| SMILES | CC(=O)OC1=C(C=CC(=C1)C(F)(F)F)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1332032 |
