Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10046767HBVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30004885HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30016238HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30003676HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30008618HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30008619HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30003677HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30018705HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30060695HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TVIS30060696HIVENSG00000109320.14protein_codingNFKB1NoNo4790P19838
TCGA Plot Options
Drug Information
GeneNFKB1
DrugBank IDDB01411
Drug NamePranlukast
Target IDBE0001086
UniProt IDP19838
Regulation Typeother/unknown
PubMed IDs12801315; 12801316
CitationsTomari S, Matsuse H, Machida I, Kondo Y, Kawano T, Obase Y, Fukushima C, Shimoda T, Kohno S: Pranlukast, a cysteinyl leukotriene receptor 1 antagonist, attenuates allergen-specific tumour necrosis factor alpha production and nuclear factor kappa B nuclear translocation in peripheral blood monocytes from atopic asthmatics. Clin Exp Allergy. 2003 Jun;33(6):795-801.@@Ichiyama T, Hasegawa S, Umeda M, Terai K, Matsubara T, Furukawa S: Pranlukast inhibits NF-kappa B activation in human monocytes/macrophages and T cells. Clin Exp Allergy. 2003 Jun;33(6):802-7.
GroupsInvestigational
Direct ClassificationChromones
SMILESO=C(NC1=C2OC(=CC(=O)C2=CC=C1)C1=NNN=N1)C1=CC=C(OCCCCC2=CC=CC=C2)C=C1
Pathways
PharmGKBPA134698661
ChEMBLCHEMBL21333