| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44018347 | HTLV-1 | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
| TVIS44036752 | HTLV-1 | ENSG00000093010.15 | protein_coding | COMT | No | No | 1312 | P21964 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | COMT |
|---|---|
| DrugBank ID | DB11632 |
| Drug Name | Opicapone |
| Target ID | BE0002089 |
| UniProt ID | P21964 |
| Regulation Type | inhibitor |
| PubMed IDs | 27498199; 16690967 |
| Citations | Scott LJ: Opicapone: A Review in Parkinson's Disease. Drugs. 2016 Sep;76(13):1293-1300. doi: 10.1007/s40265-016-0623-y.@@Tardy B, Lecompte T, Boelhen F, Tardy-Poncet B, Elalamy I, Morange P, Gruel Y, Wolf M, Francois D, Racadot E, Camarasa P, Blouch MT, Nguyen F, Doubine S, Dutrillaux F, Alhenc-Gelas M, Martin-Toutain I, Bauters A, Ffrench P, de Maistre E, Grunebaum L, Mouton C, Huisse MG, Gouault-Heilmann M, Lucke V: Predictive factors for thrombosis and major bleeding in an observational study in 181 patients with heparin-induced thrombocytopenia treated with lepirudin. Blood. 2006 Sep 1;108(5):1492-6. Epub 2006 May 11. |
| Groups | Approved; Investigational |
| Direct Classification | Phenyloxadiazoles |
| SMILES | CC1=C(C2=NOC(=N2)C2=CC(=C(O)C(O)=C2)[N+]([O-])=O)C(Cl)=[N+]([O-])C(C)=C1Cl |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1089318 |
