| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017944 | HBV | ENSG00000037280.16 | protein_coding | FLT4 | Yes | No | 2324 | P35916 |
| TVIS20039575 | HPV | ENSG00000037280.16 | protein_coding | FLT4 | Yes | No | 2324 | P35916 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FLT4 |
|---|---|
| DrugBank ID | DB09078 |
| Drug Name | Lenvatinib |
| Target ID | BE0000023 |
| UniProt ID | P35916 |
| Regulation Type | inhibitor |
| PubMed IDs | 17943726 |
| Citations | Matsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T, Uenaka T, Asada M: E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition. Int J Cancer. 2008 Feb 1;122(3):664-71. |
| Groups | Approved; Investigational |
| Direct Classification | Quinoline carboxamides |
| SMILES | COC1=C(C=C2C(OC3=CC=C(NC(=O)NC4CC4)C(Cl)=C3)=CC=NC2=C1)C(N)=O |
| Pathways | |
| PharmGKB | PA166153472 |
| ChEMBL | CHEMBL1289601 |
