| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017944 | HBV | ENSG00000037280.16 | protein_coding | FLT4 | Yes | No | 2324 | P35916 |
| TVIS20039575 | HPV | ENSG00000037280.16 | protein_coding | FLT4 | Yes | No | 2324 | P35916 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | FLT4 |
|---|---|
| DrugBank ID | DB06626 |
| Drug Name | Axitinib |
| Target ID | BE0000023 |
| UniProt ID | P35916 |
| Regulation Type | inhibitor |
| PubMed IDs | 18541897 |
| Citations | Cohen EE, Rosen LS, Vokes EE, Kies MS, Forastiere AA, Worden FP, Kane MA, Sherman E, Kim S, Bycott P, Tortorici M, Shalinsky DR, Liau KF, Cohen RB: Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study. J Clin Oncol. 2008 Oct 10;26(29):4708-13. doi: 10.1200/JCO.2007.15.9566. Epub 2008 Jun 9. |
| Groups | Approved; Investigational |
| Direct Classification | Diarylthioethers |
| SMILES | CNC(=O)C1=C(SC2=CC=C3C(NN=C3C=CC3=CC=CC=N3)=C2)C=CC=C1 |
| Pathways | |
| PharmGKB | PA164924493 |
| ChEMBL | CHEMBL1289926 |
