| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000653 | EBV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30013028 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30078106 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055932 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055933 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055934 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055935 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055936 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055937 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055938 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PPARA |
|---|---|
| DrugBank ID | DB01118 |
| Drug Name | Amiodarone |
| Target ID | BE0000071 |
| UniProt ID | Q07869 |
| Regulation Type | agonist |
| PubMed IDs | 24489787; 15265979 |
| Citations | Szalowska E, van der Burg B, Man HY, Hendriksen PJ, Peijnenburg AA: Model steatogenic compounds (amiodarone, valproic acid, and tetracycline) alter lipid metabolism by different mechanisms in mouse liver slices. PLoS One. 2014 Jan 29;9(1):e86795. doi: 10.1371/journal.pone.0086795. eCollection 2014.@@McCarthy TC, Pollak PT, Hanniman EA, Sinal CJ: Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation. J Pharmacol Exp Ther. 2004 Dec;311(3):864-73. doi: 10.1124/jpet.104.072785. Epub 2004 Jul 20. |
| Groups | Approved; Investigational |
| Direct Classification | Aryl-phenylketones |
| SMILES | CCCCC1=C(C(=O)C2=CC(I)=C(OCCN(CC)CC)C(I)=C2)C2=C(O1)C=CC=C2 |
| Pathways | Amiodarone Action Pathway |
| PharmGKB | PA448383 |
| ChEMBL | CHEMBL633 |
