| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000653 | EBV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30013028 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30078106 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055932 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055933 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055934 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055935 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055936 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055937 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055938 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PPARA |
|---|---|
| DrugBank ID | DB01708 |
| Drug Name | Prasterone |
| Target ID | BE0000071 |
| UniProt ID | Q07869 |
| Regulation Type | activator |
| PubMed IDs | 17591676; 18079279 |
| Citations | Kohalmy K, Tamasi V, Kobori L, Sarvary E, Pascussi JM, Porrogi P, Rozman D, Prough RA, Meyer UA, Monostory K: Dehydroepiandrosterone induces human CYP2B6 through the constitutive androstane receptor. Drug Metab Dispos. 2007 Sep;35(9):1495-501. Epub 2007 Jun 25.@@Tamasi V, Miller KK, Ripp SL, Vila E, Geoghagen TE, Prough RA: Modulation of receptor phosphorylation contributes to activation of peroxisome proliferator activated receptor alpha by dehydroepiandrosterone and other peroxisome proliferators. Mol Pharmacol. 2008 Mar;73(3):968-76. Epub 2007 Dec 13. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Androgens and derivatives |
| SMILES | [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@]([H])(O)CC[C@]12C |
| Pathways | |
| PharmGKB | PA451993 |
| ChEMBL | CHEMBL90593 |
