| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44015550 | HTLV-1 | ENSG00000203747.13 | protein_coding | FCGR3A | No | No | 2214 | P08637 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FCGR3A |
|---|---|
| DrugBank ID | DB12023 |
| Drug Name | Benralizumab |
| Target ID | BE0002097 |
| UniProt ID | P08637 |
| Regulation Type | binding |
| PubMed IDs | 22136436; 23866823; 28109128 |
| Citations | Ghazi A, Trikha A, Calhoun WJ: Benralizumab--a humanized mAb to IL-5Ralpha with enhanced antibody-dependent cell-mediated cytotoxicity--a novel approach for the treatment of asthma. Expert Opin Biol Ther. 2012 Jan;12(1):113-8. doi: 10.1517/14712598.2012.642359. Epub 2011 Dec 5.@@Laviolette M, Gossage DL, Gauvreau G, Leigh R, Olivenstein R, Katial R, Busse WW, Wenzel S, Wu Y, Datta V, Kolbeck R, Molfino NA: Effects of benralizumab on airway eosinophils in asthmatic patients with sputum eosinophilia. J Allergy Clin Immunol. 2013 Nov;132(5):1086-1096.e5. doi: 10.1016/j.jaci.2013.05.020. Epub 2013 Jul 16.@@Wang B, Yan L, Yao Z, Roskos LK: Population Pharmacokinetics and Pharmacodynamics of Benralizumab in Healthy Volunteers and Patients With Asthma. CPT Pharmacometrics Syst Pharmacol. 2017 Apr;6(4):249-257. doi: 10.1002/psp4.12160. Epub 2017 Jan 21. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
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| ChEMBL |
