Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44015550HTLV-1ENSG00000203747.13protein_codingFCGR3ANoNo2214P08637
TCGA Plot Options
Drug Information
GeneFCGR3A
DrugBank IDDB00002
Drug NameCetuximab
Target IDBE0002097
UniProt IDP08637
Regulation Typebinder
PubMed IDs17139284; 17016423; 17704420
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Zhang W, Gordon M, Schultheis AM, Yang DY, Nagashima F, Azuma M, Chang HM, Borucka E, Lurje G, Sherrod AE, Iqbal S, Groshen S, Lenz HJ: FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab. J Clin Oncol. 2007 Aug 20;25(24):3712-8.
GroupsApproved
Direct ClassificationPeptides
SMILES
PathwaysCetuximab Action Pathway
PharmGKBPA10040
ChEMBLCHEMBL1201577