VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS44015550 | HTLV-1 | ENSG00000203747.13 | protein_coding | FCGR3A | No | No | 2214 | P08637 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | FCGR3A |
---|---|
DrugBank ID | DB00002 |
Drug Name | Cetuximab |
Target ID | BE0002097 |
UniProt ID | P08637 |
Regulation Type | binder |
PubMed IDs | 17139284; 17016423; 17704420 |
Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Zhang W, Gordon M, Schultheis AM, Yang DY, Nagashima F, Azuma M, Chang HM, Borucka E, Lurje G, Sherrod AE, Iqbal S, Groshen S, Lenz HJ: FCGR2A and FCGR3A polymorphisms associated with clinical outcome of epidermal growth factor receptor expressing metastatic colorectal cancer patients treated with single-agent cetuximab. J Clin Oncol. 2007 Aug 20;25(24):3712-8. |
Groups | Approved |
Direct Classification | Peptides |
SMILES | |
Pathways | Cetuximab Action Pathway |
PharmGKB | PA10040 |
ChEMBL | CHEMBL1201577 |