Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20060039HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20059581HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS44012693HTLV-1ENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS44025464HTLV-1ENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS44048911HTLV-1ENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TCGA Plot Options
Drug Information
GeneGRIA1
DrugBank IDDB08883
Drug NamePerampanel
Target IDBE0000640
UniProt IDP42261
Regulation Typeantagonist
PubMed IDs21635236
CitationsHanada T, Hashizume Y, Tokuhara N, Takenaka O, Kohmura N, Ogasawara A, Hatakeyama S, Ohgoh M, Ueno M, Nishizawa Y: Perampanel: a novel, orally active, noncompetitive AMPA-receptor antagonist that reduces seizure activity in rodent models of epilepsy. Epilepsia. 2011 Jul;52(7):1331-40. doi: 10.1111/j.1528-1167.2011.03109.x. Epub 2011 Jun 2.
GroupsApproved
Direct ClassificationBipyridines and oligopyridines
SMILESO=C1N(C=C(C=C1C1=CC=CC=C1C#N)C1=NC=CC=C1)C1=CC=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL1214124