Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20060039HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS20059581HPVENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS44012693HTLV-1ENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS44025464HTLV-1ENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TVIS44048911HTLV-1ENSG00000155511.19protein_codingGRIA1NoNo2890P42261
TCGA Plot Options
Drug Information
GeneGRIA1
DrugBank IDDB00555
Drug NameLamotrigine
Target IDBE0000640
UniProt IDP42261
Regulation Typeinhibitor
PubMed IDs23976856; 22564541
CitationsLapidus KA, Soleimani L, Murrough JW: Novel glutamatergic drugs for the treatment of mood disorders. Neuropsychiatr Dis Treat. 2013;9:1101-12. doi: 10.2147/NDT.S36689. Epub 2013 Aug 7.@@Leng Y, Fessler EB, Chuang DM: Neuroprotective effects of the mood stabilizer lamotrigine against glutamate excitotoxicity: roles of chromatin remodelling and Bcl-2 induction. Int J Neuropsychopharmacol. 2013 Apr;16(3):607-20. doi: 10.1017/S1461145712000429. Epub 2012 May 8.
GroupsApproved; Investigational
Direct ClassificationDichlorobenzenes
SMILESNC1=NC(N)=C(N=N1)C1=C(Cl)C(Cl)=CC=C1
Pathways
PharmGKBPA450164
ChEMBLCHEMBL741