| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001682 | EBV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30006844 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30012119 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30012120 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30002480 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30002481 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30006845 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30012121 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30006846 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
| TVIS30006847 | HIV | ENSG00000005844.19 | protein_coding | ITGAL | No | No | 3683 | P20701 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ITGAL |
|---|---|
| DrugBank ID | DB11611 |
| Drug Name | Lifitegrast |
| Target ID | BE0000516 |
| UniProt ID | P20701 |
| Regulation Type | antagonist |
| PubMed IDs | 27883115 |
| Citations | Paton DM: Lifitegrast: First LFA-1/ICAM-1 antagonist for treatment of dry eye disease. Drugs Today (Barc). 2016 Sep;52(9):485-493. |
| Groups | Approved |
| Direct Classification | Phenylalanine and derivatives |
| SMILES | CS(=O)(=O)C1=CC(C[C@H](NC(=O)C2=C(Cl)C3=C(CN(CC3)C(=O)C3=CC=C4C=COC4=C3)C=C2Cl)C(O)=O)=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL2048028 |
