| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44048745 | HTLV-1 | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | TACR1 |
|---|---|
| DrugBank ID | DB09291 |
| Drug Name | Rolapitant |
| Target ID | BE0000384 |
| UniProt ID | P25103 |
| Regulation Type | antagonist |
| PubMed IDs | 22497992 |
| Citations | Duffy RA, Morgan C, Naylor R, Higgins GA, Varty GB, Lachowicz JE, Parker EM: Rolapitant (SCH 619734): a potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets. Pharmacol Biochem Behav. 2012 Jul;102(1):95-100. doi: 10.1016/j.pbb.2012.03.021. Epub 2012 Mar 31. |
| Groups | Approved; Investigational |
| Direct Classification | Delta amino acids and derivatives |
| SMILES | C[C@@H](OC[C@]1(CC[C@]2(CCC(=O)N2)CN1)C1=CC=CC=C1)C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3707331 |
