| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44048745 | HTLV-1 | ENSG00000115353.11 | protein_coding | TACR1 | No | No | 6869 | P25103 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TACR1 |
|---|---|
| DrugBank ID | DB12436 |
| Drug Name | Vofopitant |
| Target ID | BE0000384 |
| UniProt ID | P25103 |
| Regulation Type | |
| PubMed IDs | 21229983 |
| Citations | Di Fabio R, Alvaro G, Griffante C, Pizzi DA, Donati D, Mattioli M, Cimarosti Z, Guercio G, Marchioro C, Provera S, Zonzini L, Montanari D, Melotto S, Gerrard PA, Trist DG, Ratti E, Corsi M: Discovery and biological characterization of (2R,4S)-1'-acetyl-N-{(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2- methylphenyl)-N-methyl-4,4'-bipiperidine-1-carboxamide as a new potent and selective neurokinin 1 (NK1) receptor antagonist clinical candidate. J Med Chem. 2011 Feb 24;54(4):1071-9. doi: 10.1021/jm1013264. Epub 2011 Jan 13. |
| Groups | Investigational |
| Direct Classification | Phenylpiperidines |
| SMILES | COC1=CC=C(C=C1CN[C@H]1CCCN[C@H]1C1=CC=CC=C1)N1N=NN=C1C(F)(F)F |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL522302 |
