| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30011016 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30088012 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30086818 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30076758 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30077839 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30067852 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30067853 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30067854 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30067855 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
| TVIS30067856 | HIV | ENSG00000001626.18 | protein_coding | CFTR | No | No | 1080 | P13569 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CFTR |
|---|---|
| DrugBank ID | DB09280 |
| Drug Name | Lumacaftor |
| Target ID | BE0001195 |
| UniProt ID | P13569 |
| Regulation Type | modulator |
| PubMed IDs | 26416827 |
| Citations | Kuk K, Taylor-Cousar JL: Lumacaftor and ivacaftor in the management of patients with cystic fibrosis: current evidence and future prospects. Ther Adv Respir Dis. 2015 Dec;9(6):313-26. doi: 10.1177/1753465815601934. Epub 2015 Sep 28. |
| Groups | Approved |
| Direct Classification | Phenylpyridines |
| SMILES | CC1=CC=C(NC(=O)C2(CC2)C2=CC=C3OC(F)(F)OC3=C2)N=C1C1=CC(=CC=C1)C(O)=O |
| Pathways | |
| PharmGKB | PA166114483 |
| ChEMBL | CHEMBL2103870 |
