| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30001788 | HIV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS30081632 | HIV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS20006328 | HPV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS20033320 | HPV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS20048781 | HPV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS20036895 | HPV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS20041222 | HPV | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
| TVIS44004709 | HTLV-1 | ENSG00000148680.16 | protein_coding | HTR7 | No | No | 3363 | P34969 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR7 |
|---|---|
| DrugBank ID | DB00589 |
| Drug Name | Lisuride |
| Target ID | BE0000650 |
| UniProt ID | P34969 |
| Regulation Type | |
| PubMed IDs | 18996971; 19509219 |
| Citations | Knight JA, Smith C, Toohey N, Klein MT, Teitler M: Pharmacological analysis of the novel, rapid, and potent inactivation of the human 5-Hydroxytryptamine7 receptor by risperidone, 9-OH-Risperidone, and other inactivating antagonists. Mol Pharmacol. 2009 Feb;75(2):374-80. doi: 10.1124/mol.108.052084. Epub 2008 Nov 7.@@Toohey N, Klein MT, Knight J, Smith C, Teitler M: Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other "inactivating antagonists". Mol Pharmacol. 2009 Sep;76(3):552-9. doi: 10.1124/mol.109.056283. Epub 2009 Jun 9. |
| Groups | Approved; Investigational |
| Direct Classification | Indoloquinolines |
| SMILES | [H][C@@]12CC3=CNC4=CC=CC(=C34)C1=C[C@@H](CN2C)NC(=O)N(CC)CC |
| Pathways | |
| PharmGKB | PA164749019 |
| ChEMBL | CHEMBL157138 |
