| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048171 | HBV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30004651 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30004652 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30002798 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30007200 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30007201 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30007202 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30075419 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30075420 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
| TVIS30075421 | HIV | ENSG00000154229.12 | protein_coding | PRKCA | No | No | 5578 | P17252 Q7Z727 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PRKCA |
|---|---|
| DrugBank ID | DB14001 |
| Drug Name | alpha-Tocopherol succinate |
| Target ID | BE0001132 |
| UniProt ID | P17252 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 9430404; 11736999; 11850093 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Azzi A, Boscoboinik D, Clement S, Marilley D, Ozer NK, Ricciarelli R, Tasinato A: Alpha-tocopherol as a modulator of smooth muscle cell proliferation. Prostaglandins Leukot Essent Fatty Acids. 1997 Oct;57(4-5):507-14.@@Sylvester PW, McIntyre BS, Gapor A, Briski KP: Vitamin E inhibition of normal mammary epithelial cell growth is associated with a reduction in protein kinase C(alpha) activation. Cell Prolif. 2001 Dec;34(6):347-57.@@Huang Y, Ishizuka T, Miura A, Kajita K, Ishizawa M, Kimura M, Yamamoto Y, Kawai Y, Morita H, Uno Y, Yasuda K: Effect of 1 alpha,25-dihydroxy vitamin D3 and vitamin E on insulin-induced glucose uptake in rat adipocytes. Diabetes Res Clin Pract. 2002 Mar;55(3):175-83. |
| Groups | Approved; Nutraceutical; Vet_approved |
| Direct Classification | Vitamin E compounds |
| SMILES | [H][C@@](C)(CCCC(C)C)CCC[C@@]([H])(C)CCC[C@]1(C)CCC2=C(C)C(OC(=O)CCC(O)=O)=C(C)C(C)=C2O1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL81421 |
