| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30072183 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072184 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30020995 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072185 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072186 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072187 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072188 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072189 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS30072190 | HIV | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
| TVIS44050717 | HTLV-1 | ENSG00000097007.20 | protein_coding | ABL1 | Yes | No | 25 | P00519 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABL1 |
|---|---|
| DrugBank ID | DB12323 |
| Drug Name | Radotinib |
| Target ID | BE0000014 |
| UniProt ID | P00519 |
| Regulation Type | antagonist |
| PubMed IDs | 24705186 |
| Citations | Kim SH, Menon H, Jootar S, Saikia T, Kwak JY, Sohn SK, Park JS, Jeong SH, Kim HJ, Kim YK, Oh SJ, Kim H, Zang DY, Chung JS, Shin HJ, Do YR, Kim JA, Kim DY, Choi CW, Park S, Park HL, Lee GY, Cho DJ, Shin JS, Kim DW: Efficacy and safety of radotinib in chronic phase chronic myeloid leukemia patients with resistance or intolerance to BCR-ABL1 tyrosine kinase inhibitors. Haematologica. 2014 Jul;99(7):1191-6. doi: 10.3324/haematol.2013.096776. Epub 2014 Apr 4. |
| Groups | Investigational |
| Direct Classification | Benzanilides |
| SMILES | CC1=CN(C=N1)C1=CC(NC(=O)C2=CC=C(C)C(NC3=NC=CC(=N3)C3=CN=CC=N3)=C2)=CC(=C1)C(F)(F)F |
| Pathways | |
| PharmGKB | |
| ChEMBL |
