| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30011232 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30011233 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023050 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023051 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023052 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023053 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023054 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023055 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023056 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
| TVIS30023057 | HIV | ENSG00000116478.13 | protein_coding | HDAC1 | Yes | No | 3065 | Q13547 Q6IT96 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | HDAC1 |
|---|---|
| DrugBank ID | DB12645 |
| Drug Name | Givinostat |
| Target ID | BE0008667 |
| UniProt ID | Q9UKV0 |
| Regulation Type | inhibitor |
| PubMed IDs | 33936902; 32503121 |
| Citations | Arya Y, Syal A, Gupta M, Gaba S: Advances in the Treatment of Polycythemia Vera: Trends in Disease Management. Cureus. 2021 Mar 30;13(3):e14193. doi: 10.7759/cureus.14193.@@Curreli F, Ahmed S, Victor SMB, Debnath AK: Identification of Combinations of Protein Kinase C Activators and Histone Deacetylase Inhibitors That Potently Reactivate Latent HIV. Viruses. 2020 Jun 3;12(6). pii: v12060609. doi: 10.3390/v12060609. |
| Groups | Investigational |
| Direct Classification | Phenylcarbamic acid esters |
| SMILES | CCN(CC)CC1=CC=C2C=C(COC(=O)NC3=CC=C(C=C3)C(=O)NO)C=CC2=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL1213492 |
