| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10007053 | HBV | ENSG00000128052.10 | protein_coding | KDR | Yes | No | 3791 | P35968 |
| TVIS10007054 | HBV | ENSG00000128052.10 | protein_coding | KDR | Yes | No | 3791 | P35968 |
| TVIS10016656 | HBV | ENSG00000128052.10 | protein_coding | KDR | Yes | No | 3791 | P35968 |
| TVIS10000123 | HBV | ENSG00000128052.10 | protein_coding | KDR | Yes | No | 3791 | P35968 |
| TVIS20058066 | HPV | ENSG00000128052.10 | protein_coding | KDR | Yes | No | 3791 | P35968 |
| TVIS44025335 | HTLV-1 | ENSG00000128052.10 | protein_coding | KDR | Yes | No | 3791 | P35968 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KDR |
|---|---|
| DrugBank ID | DB06626 |
| Drug Name | Axitinib |
| Target ID | BE0000369 |
| UniProt ID | P35968 |
| Regulation Type | inhibitor |
| PubMed IDs | 18541897 |
| Citations | Cohen EE, Rosen LS, Vokes EE, Kies MS, Forastiere AA, Worden FP, Kane MA, Sherman E, Kim S, Bycott P, Tortorici M, Shalinsky DR, Liau KF, Cohen RB: Axitinib is an active treatment for all histologic subtypes of advanced thyroid cancer: results from a phase II study. J Clin Oncol. 2008 Oct 10;26(29):4708-13. doi: 10.1200/JCO.2007.15.9566. Epub 2008 Jun 9. |
| Groups | Approved; Investigational |
| Direct Classification | Diarylthioethers |
| SMILES | CNC(=O)C1=C(SC2=CC=C3C(NN=C3C=CC3=CC=CC=N3)=C2)C=CC=C1 |
| Pathways | |
| PharmGKB | PA164924493 |
| ChEMBL | CHEMBL1289926 |
