Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10007053HBVENSG00000128052.10protein_codingKDRYesNo3791P35968
TVIS10007054HBVENSG00000128052.10protein_codingKDRYesNo3791P35968
TVIS10016656HBVENSG00000128052.10protein_codingKDRYesNo3791P35968
TVIS10000123HBVENSG00000128052.10protein_codingKDRYesNo3791P35968
TVIS20058066HPVENSG00000128052.10protein_codingKDRYesNo3791P35968
TVIS44025335HTLV-1ENSG00000128052.10protein_codingKDRYesNo3791P35968
TCGA Plot Options
Drug Information
GeneKDR
DrugBank IDDB04849
Drug NameCediranib
Target IDBE0000369
UniProt IDP35968
Regulation Type
PubMed IDs15899831
CitationsWedge SR, Kendrew J, Hennequin LF, Valentine PJ, Barry ST, Brave SR, Smith NR, James NH, Dukes M, Curwen JO, Chester R, Jackson JA, Boffey SJ, Kilburn LL, Barnett S, Richmond GH, Wadsworth PF, Walker M, Bigley AL, Taylor ST, Cooper L, Beck S, Jurgensmeier JM, Ogilvie DJ: AZD2171: a highly potent, orally bioavailable, vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor for the treatment of cancer. Cancer Res. 2005 May 15;65(10):4389-400.
GroupsInvestigational
Direct ClassificationDiarylethers
SMILESCOC1=CC2=C(C=C1OCCCN1CCCC1)N=CN=C2OC1=C(F)C2=C(NC(C)=C2)C=C1
Pathways
PharmGKB
ChEMBLCHEMBL491473