No data available for the specified gene.
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HDAC1 |
|---|---|
| DrugBank ID | DB12847 |
| Drug Name | Pyroxamide |
| Target ID | BE0008667 |
| UniProt ID | Q9UKV0 |
| Regulation Type | inhibitor |
| PubMed IDs | 11309347; 16391874; 12678732 |
| Citations | Butler LM, Webb Y, Agus DB, Higgins B, Tolentino TR, Kutko MC, LaQuaglia MP, Drobnjak M, Cordon-Cardo C, Scher HI, Breslow R, Richon VM, Rifkind RA, Marks PA: Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase. Clin Cancer Res. 2001 Apr;7(4):962-70.@@Kouraklis G, Theocharis S: Histone deacetylase inhibitors: a novel target of anticancer therapy (review). Oncol Rep. 2006 Feb;15(2):489-94.@@Kouraklis G, Theocharis S: Histone deacetylase inhibitors and anticancer therapy. Curr Med Chem Anticancer Agents. 2002 Jul;2(4):477-84. doi: 10.2174/1568011023353921. |
| Groups | Investigational |
| Direct Classification | Pyridines and derivatives |
| SMILES | ONC(=O)CCCCCCC(=O)NC1=CN=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL353581 |
