| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20052473 | HPV | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
| TVIS20046137 | HPV | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
| TVIS44023827 | HTLV-1 | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
| TVIS44047437 | HTLV-1 | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABAT |
|---|---|
| DrugBank ID | DB00119 |
| Drug Name | Pyruvic acid |
| Target ID | BE0000253 |
| UniProt ID | P80404 |
| Regulation Type | inhibitor |
| PubMed IDs | 17355287; 16435204; 11752352 |
| Citations | Andersen G, Andersen B, Dobritzsch D, Schnackerz KD, Piskur J: A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast. FEBS J. 2007 Apr;274(7):1804-17. Epub 2007 Mar 12.@@Schmidt C, Hofmann U, Kohlmuller D, Murdter T, Zanger UM, Schwab M, Hoffmann GF: Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry. J Inherit Metab Dis. 2005;28(6):1109-22.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Alpha-keto acids and derivatives |
| SMILES | CC(=O)C(O)=O |
| Pathways | Citrullinemia Type I; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Glycogenosis, Type IB; Argininemia; Pyruvate Kinase Deficiency; Pyruvate Carboxylase Deficiency; Amino Sugar Metabolism; The Oncogenic Action of Fumarate; 3-Phosphoglycerate Dehydrogenase Deficiency; Glycolysis; Non-Ketotic Hyperglycinemia; 2-Hydroxyglutric Aciduria (D and L Form); Glucose-Alanine Cycle; G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease; Alanine Metabolism; Hyperglycinemia, Non-Ketotic; Cystinosis, Ocular Nonnephropathic; Dimethylglycine Dehydrogenase Deficiency; Glycogenosis, Type VII. Tarui Disease; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Lactic Acidemia; Homocarnosinosis; Primary Hyperoxaluria Type I; Ornithine Transcarbamylase Deficiency (OTC Deficiency); The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxygluaricaciduria; Sarcosinemia; Urea Cycle; Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1); Cysteine Metabolism |
| PharmGKB | PA164778686 |
| ChEMBL | CHEMBL1162144 |
