| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20052473 | HPV | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
| TVIS20046137 | HPV | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
| TVIS44023827 | HTLV-1 | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
| TVIS44047437 | HTLV-1 | ENSG00000183044.12 | protein_coding | ABAT | No | No | 18 | P80404 X5D8S1 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABAT |
|---|---|
| DrugBank ID | DB00780 |
| Drug Name | Phenelzine |
| Target ID | BE0000253 |
| UniProt ID | P80404 |
| Regulation Type | inhibitor |
| PubMed IDs | 17768678; 11775064; 7931216; 1610412; 8749840; 19203467; 1881457 |
| Citations | MacKenzie EM, Grant SL, Baker GB, Wood PL: Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. Neurochem Res. 2008 Mar;33(3):430-6. Epub 2007 Aug 31.@@Tanay VA, Parent MB, Wong JT, Paslawski T, Martin IL, Baker GB: Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain. Cell Mol Neurobiol. 2001 Aug;21(4):325-39.@@McKenna KF, McManus DJ, Baker GB, Coutts RT: Chronic administration of the antidepressant phenelzine and its N-acetyl analogue: effects on GABAergic function. J Neural Transm Suppl. 1994;41:115-22.@@McManus DJ, Baker GB, Martin IL, Greenshaw AJ, McKenna KF: Effects of the antidepressant/antipanic drug phenelzine on GABA concentrations and GABA-transaminase activity in rat brain. Biochem Pharmacol. 1992 Jun 9;43(11):2486-9.@@Todd KG, Baker GB: GABA-elevating effects of the antidepressant/antipanic drug phenelzine in brain: effects of pretreatment with tranylcypromine, (-)-deprenyl and clorgyline. J Affect Disord. 1995 Dec 13;35(3):125-9.@@Todd KG, Baker GB: Neurochemical effects of the monoamine oxidase inhibitor phenelzine on brain GABA and alanine: A comparison with vigabatrin. J Pharm Pharm Sci. 2008 May 16;11(2):14s-21s.@@McKenna KF, Baker GB, Coutts RT: N2-acetylphenelzine: effects on rat brain GABA, alanine and biogenic amines. Naunyn Schmiedebergs Arch Pharmacol. 1991 May;343(5):478-82. |
| Groups | Approved |
| Direct Classification | Benzene and substituted derivatives |
| SMILES | NNCCC1=CC=CC=C1 |
| Pathways | |
| PharmGKB | PA450903 |
| ChEMBL | CHEMBL1089 |
