| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20018154 | HPV | ENSG00000004846.17 | protein_coding | ABCB5 | No | No | 340273 | Q2M3G0 |
| TVIS20018155 | HPV | ENSG00000004846.17 | protein_coding | ABCB5 | No | No | 340273 | Q2M3G0 |
| TVIS44014902 | HTLV-1 | ENSG00000004846.17 | protein_coding | ABCB5 | No | No | 340273 | Q2M3G0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABCB5 |
|---|---|
| DrugBank ID | DB14067 |
| Drug Name | Dofequidar |
| Target ID | BE0002369 |
| UniProt ID | Q2M3G0 |
| Regulation Type | inhibitor |
| PubMed IDs | 26870817 |
| Citations | Katayama R, Sakashita T, Yanagitani N, Ninomiya H, Horiike A, Friboulet L, Gainor JF, Motoi N, Dobashi A, Sakata S, Tambo Y, Kitazono S, Sato S, Koike S, John Iafrate A, Mino-Kenudson M, Ishikawa Y, Shaw AT, Engelman JA, Takeuchi K, Nishio M, Fujita N: P-glycoprotein Mediates Ceritinib Resistance in Anaplastic Lymphoma Kinase-rearranged Non-small Cell Lung Cancer. EBioMedicine. 2015 Dec 12;3:54-66. doi: 10.1016/j.ebiom.2015.12.009. eCollection 2016 Jan. |
| Groups | Experimental; Investigational |
| Direct Classification | |
| SMILES | OC(COC1=CC=CC2=C1C=CC=N2)CN1CCN(CC1)C(=O)C(C1=CC=CC=C1)C1=CC=CC=C1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL65067 |
