Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS46001196BKPyvENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS42000292EBVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS10011755HBVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS10034856HBVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS30066652HIVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS30066653HIVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS30066654HIVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS20000392HPVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS20000679HPVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TVIS20005627HPVENSG00000004846.17protein_codingABCB5NoNo340273Q2M3G0
TCGA Plot Options
Drug Information
GeneABCB5
DrugBank IDDB04851
Drug NameBiricodar
Target IDBE0002369
UniProt IDQ2M3G0
Regulation Type
PubMed IDs15014037
CitationsMinderman H, O'Loughlin KL, Pendyala L, Baer MR: VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Clin Cancer Res. 2004 Mar 1;10(5):1826-34.
GroupsInvestigational
Direct Classification
SMILESCOC1=CC(=CC(OC)=C1OC)C(=O)C(=O)N1CCCC[C@H]1C(=O)OC(CCCC1=CN=CC=C1)CCCC1=CN=CC=C1
Pathways
PharmGKBPA164924560
ChEMBLCHEMBL350775