| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10041216 | HBV | ENSG00000248144.6 | protein_coding | ADH1C | No | No | 126 | P00326 |
| TVIS10041217 | HBV | ENSG00000248144.6 | protein_coding | ADH1C | No | No | 126 | P00326 |
| TVIS30060584 | HIV | ENSG00000248144.6 | protein_coding | ADH1C | No | No | 126 | P00326 |
| TVIS20040351 | HPV | ENSG00000248144.6 | protein_coding | ADH1C | No | No | 126 | P00326 |
| TVIS20013019 | HPV | ENSG00000248144.6 | protein_coding | ADH1C | No | No | 126 | P00326 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADH1C |
|---|---|
| DrugBank ID | DB01213 |
| Drug Name | Fomepizole |
| Target ID | BE0000465 |
| UniProt ID | P00326 |
| Regulation Type | inhibitor |
| PubMed IDs | 11391066; 19458366; 16871118; 16946442 |
| Citations | Eriksson CJ, Fukunaga T, Sarkola T, Chen WJ, Chen CC, Ju JM, Cheng AT, Yamamoto H, Kohlenberg-Muller K, Kimura M, Murayama M, Matsushita S, Kashima H, Higuchi S, Carr L, Viljoen D, Brooke L, Stewart T, Foroud T, Su J, Li TK, Whitfield JB: Functional relevance of human adh polymorphism. Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):157S-163S.@@Brent J: Fomepizole for ethylene glycol and methanol poisoning. N Engl J Med. 2009 May 21;360(21):2216-23. doi: 10.1056/NEJMct0806112.@@Calello DP, Osterhoudt KC, Henretig FM: New and novel antidotes in pediatrics. Pediatr Emerg Care. 2006 Jul;22(7):523-30.@@Betten DP, Vohra RB, Cook MD, Matteucci MJ, Clark RF: Antidote use in the critically ill poisoned patient. J Intensive Care Med. 2006 Sep-Oct;21(5):255-77. |
| Groups | Approved; Vet_approved |
| Direct Classification | Pyrazoles |
| SMILES | CC1=CNN=C1 |
| Pathways | |
| PharmGKB | PA449697 |
| ChEMBL | CHEMBL1308 |
