| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10062361 | HBV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30009250 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30014148 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30009251 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30009252 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30009253 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30085711 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30081803 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30019304 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
| TVIS30088721 | HIV | ENSG00000106546.14 | protein_coding | AHR | No | No | 196 | P35869 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | AHR |
|---|---|
| DrugBank ID | DB00379 |
| Drug Name | Mexiletine |
| Target ID | BE0003721 |
| UniProt ID | P35869 |
| Regulation Type | agonist |
| PubMed IDs | 17327465 |
| Citations | Hu W, Sorrentino C, Denison MS, Kolaja K, Fielden MR: Induction of cyp1a1 is a nonspecific biomarker of aryl hydrocarbon receptor activation: results of large scale screening of pharmaceuticals and toxicants in vivo and in vitro. Mol Pharmacol. 2007 Jun;71(6):1475-86. Epub 2007 Feb 27. |
| Groups | Approved; Investigational |
| Direct Classification | Phenol ethers |
| SMILES | CC(N)COC1=C(C)C=CC=C1C |
| Pathways | Mexiletine Action Pathway |
| PharmGKB | PA450488 |
| ChEMBL | CHEMBL558 |
