| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20043167 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20055124 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20045061 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20054251 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20055059 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20054259 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20055046 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20041515 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20018853 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
| TVIS20055117 | HPV | ENSG00000171094.18 | protein_coding | ALK | Yes | No | 238 | B6D4Y2 Q9UM73 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | ALK |
|---|---|
| DrugBank ID | DB08865 |
| Drug Name | Crizotinib |
| Target ID | BE0000359 |
| UniProt ID | Q9UM73 |
| Regulation Type | inhibitor |
| PubMed IDs | 22594847 |
| Citations | Forde PM, Rudin CM: Crizotinib in the treatment of non-small-cell lung cancer. Expert Opin Pharmacother. 2012 Jun;13(8):1195-201. doi: 10.1517/14656566.2012.688029. |
| Groups | Approved; Investigational |
| Direct Classification | Pyrazolylpyridines |
| SMILES | C[C@@H](OC1=CC(=CN=C1N)C1=CN(N=C1)C1CCNCC1)C1=C(Cl)C=CC(F)=C1Cl |
| Pathways | |
| PharmGKB | PA165946122 |
| ChEMBL | CHEMBL601719 |
