| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20029394 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030211 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20029395 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030515 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030212 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030516 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20029396 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030213 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS44027647 | HTLV-1 | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ATP4A |
|---|---|
| DrugBank ID | DB00338 |
| Drug Name | Omeprazole |
| Target ID | BE0000349 |
| UniProt ID | P20648 |
| Regulation Type | inhibitor |
| PubMed IDs | 18679668; 18925391; 18536934; 17425287; 679668; 16700898 |
| Citations | Shi S, Klotz U: Proton pump inhibitors: an update of their clinical use and pharmacokinetics. Eur J Clin Pharmacol. 2008 Oct;64(10):935-51. doi: 10.1007/s00228-008-0538-y. Epub 2008 Aug 5.@@Kirchheiner J, Glatt S, Fuhr U, Klotz U, Meineke I, Seufferlein T, Brockmoller J: Relative potency of proton-pump inhibitors-comparison of effects on intragastric pH. Eur J Clin Pharmacol. 2009 Jan;65(1):19-31. doi: 10.1007/s00228-008-0576-5. Epub 2008 Oct 17.@@Shin JM, Munson K, Vagin O, Sachs G: The gastric HK-ATPase: structure, function, and inhibition. Pflugers Arch. 2009 Jan;457(3):609-22. doi: 10.1007/s00424-008-0495-4. Epub 2008 Jun 6.@@Munson K, Law RJ, Sachs G: Analysis of the gastric H,K ATPase for ion pathways and inhibitor binding sites. Biochemistry. 2007 May 8;46(18):5398-417. doi: 10.1021/bi062305h. Epub 2007 Apr 11.@@Zuger B: Effeminate behavior present in boys from childhood: ten additional years of follow-up. Compr Psychiatry. 1978 Jul-Aug;19(4):363-9.@@Sachs G, Shin JM, Howden CW: Review article: the clinical pharmacology of proton pump inhibitors. Aliment Pharmacol Ther. 2006 Jun;23 Suppl 2:2-8. doi: 10.1111/j.1365-2036.2006.02943.x. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Sulfinylbenzimidazoles |
| SMILES | COC1=CC2=C(C=C1)N=C(N2)S(=O)CC1=NC=C(C)C(OC)=C1C |
| Pathways | Omeprazole Metabolism Pathway; Omeprazole Action Pathway |
| PharmGKB | PA10075 |
| ChEMBL | CHEMBL1503 |
