| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20029394 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030211 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20029395 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030515 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030212 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030516 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20029396 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS20030213 | HPV | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
| TVIS44027647 | HTLV-1 | ENSG00000105675.9 | protein_coding | ATP4A | No | No | 495 | P20648 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ATP4A |
|---|---|
| DrugBank ID | DB00736 |
| Drug Name | Esomeprazole |
| Target ID | BE0000349 |
| UniProt ID | P20648 |
| Regulation Type | inhibitor |
| PubMed IDs | 19606942; 18627213; 19210109; 11752352 |
| Citations | Saccar CL: The pharmacology of esomeprazole and its role in gastric acid related diseases. Expert Opin Drug Metab Toxicol. 2009 Sep;5(9):1113-24. doi: 10.1517/17425250903124363.@@McKeage K, Blick SK, Croxtall JD, Lyseng-Williamson KA, Keating GM: Esomeprazole: a review of its use in the management of gastric acid-related diseases in adults. Drugs. 2008;68(11):1571-607.@@Vachhani R, Olds G, Velanovich V: Esomeprazole: a proton pump inhibitor. Expert Rev Gastroenterol Hepatol. 2009 Feb;3(1):15-27. doi: 10.1586/17474124.3.1.15.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved; Investigational |
| Direct Classification | Sulfinylbenzimidazoles |
| SMILES | COC1=CC2=C(NC(=N2)[S@@](=O)CC2=NC=C(C)C(OC)=C2C)C=C1 |
| Pathways | Esomeprazole Action Pathway; Esomeprazole Metabolism Pathway |
| PharmGKB | PA10075 |
| ChEMBL | CHEMBL1201320 |
